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Inferring regulatory element landscapes and transcription factor networks from cancer methylomes

Recent studies indicate that DNA methylation can be used to identify transcriptional enhancers, but no systematic approach has been developed for genome-wide identification and analysis of enhancers based on DNA methylation. We describe ELMER (Enhancer Linking by Methylation/Expression Relationships...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Yao, Lijing, Shen, Hui, Laird, Peter W, Farnham, Peggy J, Berman, Benjamin P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460959/
https://ncbi.nlm.nih.gov/pubmed/25994056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0668-3
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