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Defining Regulatory Elements in the Human Genome Using Nucleosome Occupancy and Methylome Sequencing (NOMe-seq)
NOMe-seq (nucleosome occupancy and methylome sequencing) identifies nucleosome- depleted regions that correspond to promoters, enhancers, and insulators. The NOMe-seq method is based on the treatment of chromatin with the M.CviPI methyltransferase, which methylates GpC dinucleotides that are not pro...
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| 發表在: | Methods Mol Biol |
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| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2018
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6019634/ https://ncbi.nlm.nih.gov/pubmed/29605855 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7768-0_12 |
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