Nucleosome positioning and histone modifications define relationships between regulatory elements and nearby gene expression in breast epithelial cells

BACKGROUND: The precise nature of how cell type specific chromatin structures at enhancer sites affect gene expression is largely unknown. Here we identified cell type specific enhancers coupled with gene expression in two different types of breast epithelial cells, HMEC (normal breast epithelial ce...

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Главные авторы: Rhie, Suhn Kyong, Hazelett, Dennis J, Coetzee, Simon G, Yan, Chunli, Noushmehr, Houtan, Coetzee, Gerhard A
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035062/
https://ncbi.nlm.nih.gov/pubmed/24885402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-331
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