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Defining Regulatory Elements in the Human Genome Using Nucleosome Occupancy and Methylome Sequencing (NOMe-seq)

NOMe-seq (nucleosome occupancy and methylome sequencing) identifies nucleosome- depleted regions that correspond to promoters, enhancers, and insulators. The NOMe-seq method is based on the treatment of chromatin with the M.CviPI methyltransferase, which methylates GpC dinucleotides that are not pro...

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Detalles Bibliográficos
Publicado en:Methods Mol Biol
Main Authors: Rhie, Suhn Kyong, Schreiner, Shannon, Farnham, Peggy J
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6019634/
https://ncbi.nlm.nih.gov/pubmed/29605855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-7768-0_12
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