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Inferring regulatory element landscapes and transcription factor networks from cancer methylomes

Recent studies indicate that DNA methylation can be used to identify transcriptional enhancers, but no systematic approach has been developed for genome-wide identification and analysis of enhancers based on DNA methylation. We describe ELMER (Enhancer Linking by Methylation/Expression Relationships...

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Bibliografische gegevens
Gepubliceerd in:Genome Biol
Hoofdauteurs: Yao, Lijing, Shen, Hui, Laird, Peter W, Farnham, Peggy J, Berman, Benjamin P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4460959/
https://ncbi.nlm.nih.gov/pubmed/25994056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-015-0668-3
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