Identification of activated enhancers and linked transcription factors in breast, prostate, and kidney tumors by tracing enhancer networks using epigenetic traits

BACKGROUND: Although technological advances now allow increased tumor profiling, a detailed understanding of the mechanisms leading to the development of different cancers remains elusive. Our approach toward understanding the molecular events that lead to cancer is to characterize changes in transc...

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Vydáno v:Epigenetics Chromatin
Hlavní autoři: Rhie, Suhn Kyong, Guo, Yu, Tak, Yu Gyoung, Yao, Lijing, Shen, Hui, Coetzee, Gerhard A., Laird, Peter W., Farnham, Peggy J.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5103450/
https://ncbi.nlm.nih.gov/pubmed/27833659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-016-0102-4
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