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Systematic, network-based characterization of therapeutic target inhibitors
A large fraction of the proteins that are being identified as key tumor dependencies represent poor pharmacological targets or lack clinically-relevant small-molecule inhibitors. Availability of fully generalizable approaches for the systematic and efficient prioritization of tumor-context specific...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5638208/ https://ncbi.nlm.nih.gov/pubmed/29023443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005599 |
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