Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles

Degeneration of elastic lamina and vascular calcification are common features of vascular pathology such as aortic aneurysms. We tested whether dual therapy with targeted nanoparticles (NPs) can remove mineral deposits (by delivery of a chelating agent, ethylene diamine tetraacetic acid (EDTA)) and...

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Dettagli Bibliografici
Pubblicato in:Theranostics
Autori principali: Nosoudi, Nasim, Chowdhury, Aniqa, Siclari, Steven, Karamched, Saketh, Parasaram, Vaideesh, Parrish, Joe, Gerard, Patrick, Vyavahare, Narendra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Ivyspring International Publisher 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039337/
https://ncbi.nlm.nih.gov/pubmed/27698934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16547
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