Reversal of Vascular Calcification and Aneurysms in a Rat Model Using Dual Targeted Therapy with EDTA- and PGG-Loaded Nanoparticles

Degeneration of elastic lamina and vascular calcification are common features of vascular pathology such as aortic aneurysms. We tested whether dual therapy with targeted nanoparticles (NPs) can remove mineral deposits (by delivery of a chelating agent, ethylene diamine tetraacetic acid (EDTA)) and...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Nosoudi, Nasim, Chowdhury, Aniqa, Siclari, Steven, Karamched, Saketh, Parasaram, Vaideesh, Parrish, Joe, Gerard, Patrick, Vyavahare, Narendra
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5039337/
https://ncbi.nlm.nih.gov/pubmed/27698934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16547
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