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Site-specific chelation therapy with EDTA-loaded albumin nanoparticles reverses arterial calcification in a rat model of chronic kidney disease

Medial arterial calcification (MAC) is a common outcome in diabetes and chronic kidney disease (CKD). It occurs as linear mineral deposits along the degraded elastin lamellae and is responsible for increased aortic stiffness and subsequent cardiovascular events. Current treatments for calcification,...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Karamched, Saketh R., Nosoudi, Nasim, Moreland, Hannah E., Chowdhury, Aniqa, Vyavahare, Naren R.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6385348/
https://ncbi.nlm.nih.gov/pubmed/30796300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39639-8
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