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Targeted chelation therapy with EDTA-loaded albumin nanoparticles regresses arterial calcification without causing systemic side effects

BACKGROUND AND AIMS: Elastin-specific medial arterial calcification (MAC) is an arterial disease commonly referred as Monckeberg’s sclerosis. It causes significant arterial stiffness, and as yet, no clinical therapy exists to prevent or reverse it. We developed albumin nanoparticles (NPs) loaded wit...

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Bibliografski detalji
Izdano u:J Control Release
Glavni autori: Lei, Yang, Nosoudi, Nasim, Vyavahare, Naren
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4268131/
https://ncbi.nlm.nih.gov/pubmed/25285609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.09.029
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