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Targeted chelation therapy with EDTA-loaded albumin nanoparticles regresses arterial calcification without causing systemic side effects
BACKGROUND AND AIMS: Elastin-specific medial arterial calcification (MAC) is an arterial disease commonly referred as Monckeberg’s sclerosis. It causes significant arterial stiffness, and as yet, no clinical therapy exists to prevent or reverse it. We developed albumin nanoparticles (NPs) loaded wit...
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| 發表在: | J Control Release |
|---|---|
| Main Authors: | , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4268131/ https://ncbi.nlm.nih.gov/pubmed/25285609 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2014.09.029 |
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