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Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

The human brain has enormously complex cellular diversity and connectivities fundamental to our neural functions, yet difficulties in interrogating individual neurons has impeded understanding of the underlying transcriptional landscape. We developed a scalable approach to sequence and quantify RNA...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Lake, Blue B., Ai, Rizi, Kaeser, Gwendolyn E., Salathia, Neeraj S., Yung, Yun C., Liu, Rui, Wildberg, Andre, Gao, Derek, Fung, Ho-Lim, Chen, Song, Vijayaraghavan, Raakhee, Wong, Julian, Chen, Allison, Sheng, Xiaoyan, Kaper, Fiona, Shen, Richard, Ronaghi, Mostafa, Fan, Jian-Bing, Wang, Wei, Chun, Jerold, Zhang, Kun
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038589/
https://ncbi.nlm.nih.gov/pubmed/27339989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf1204
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