Neuronal subtypes and diversity revealed by single-nucleus RNA sequencing of the human brain

The human brain has enormously complex cellular diversity and connectivities fundamental to our neural functions, yet difficulties in interrogating individual neurons has impeded understanding of the underlying transcriptional landscape. We developed a scalable approach to sequence and quantify RNA...

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Published in:Science
Main Authors: Lake, Blue B., Ai, Rizi, Kaeser, Gwendolyn E., Salathia, Neeraj S., Yung, Yun C., Liu, Rui, Wildberg, Andre, Gao, Derek, Fung, Ho-Lim, Chen, Song, Vijayaraghavan, Raakhee, Wong, Julian, Chen, Allison, Sheng, Xiaoyan, Kaper, Fiona, Shen, Richard, Ronaghi, Mostafa, Fan, Jian-Bing, Wang, Wei, Chun, Jerold, Zhang, Kun
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038589/
https://ncbi.nlm.nih.gov/pubmed/27339989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aaf1204
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