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Characterizing transcriptional heterogeneity through pathway and gene set overdispersion analysis

The transcriptional state of a cell reflects a variety of biological factors, from persistent cell-type specific features to transient processes such as cell cycle. Depending on biological context, all such aspects of transcriptional heterogeneity may be of interest, but detecting them from noisy si...

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Publicat a:Nat Methods
Autors principals: Fan, Jean, Salathia, Neeraj, Liu, Rui, Kaeser, Gwendolyn E., Yung, Yun C., Herman, Joseph L., Kaper, Fiona, Fan, Jian-Bing, Zhang, Kun, Chun, Jerold, Kharchenko, Peter V.
Format: Artigo
Idioma:Inglês
Publicat: 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772672/
https://ncbi.nlm.nih.gov/pubmed/26780092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.3734
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