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Brain cell somatic gene recombination and its phylogenetic foundations

A new form of somatic gene recombination (SGR) has been identified in the human brain that affects the Alzheimer's disease gene, amyloid precursor protein (APP). SGR occurs when a gene sequence is cut and recombined within a single cell's genomic DNA, generally independent of DNA replicati...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kaeser, Gwendolyn, Chun, Jerold
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7476723/
https://ncbi.nlm.nih.gov/pubmed/32699111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV120.009192
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