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Genomic Mosaicism Formed by Somatic Variation in the Aging and Diseased Brain

Over the past 20 years, analyses of single brain cell genomes have revealed that the brain is composed of cells with myriad distinct genomes: the brain is a genomic mosaic, generated by a host of DNA sequence-altering processes that occur somatically and do not affect the germline. As such, these se...

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Bibliografiset tiedot
Julkaisussa:Genes (Basel)
Päätekijät: Costantino, Isabel, Nicodemus, Juliet, Chun, Jerold
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2021
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8305509/
https://ncbi.nlm.nih.gov/pubmed/34356087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes12071071
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