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Inhibition of Leishmania mexicana Growth by the Tuberculosis Drug SQ109
We report that the tuberculosis drug SQ109 [N-adamantan-2-yl-N′-((E)-3,7-dimethyl-octa-2,6-dienyl)-ethane-1,2-diamine] has potent activity against the intracellular amastigote form of Leishmania mexicana (50% inhibitory concentration [IC(50)], ∼11 nM), with a good selectivity index (>500). It is...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5038243/ https://ncbi.nlm.nih.gov/pubmed/27458218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00945-16 |
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