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Differential Effects of Paromomycin on Ribosomes of Leishmania mexicana and Mammalian Cells

Paromomycin, an aminoglycoside antibiotic having low mammalian cell toxicity, is one of the drugs currently used in the chemotherapy of cutaneous and visceral leishmaniasis. In order to understand the mode of action of this antibiotic at the molecular level, we have investigated the effects of parom...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fernández, Marisa M., Malchiodi, Emilio L., Algranati, Israel D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019668/
https://ncbi.nlm.nih.gov/pubmed/20956601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00506-10
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