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Dronedarone, an Amiodarone Analog with Improved Anti-Leishmania mexicana Efficacy
Dronedarone and amiodarone are cationic lipophilic benzofurans used to treat cardiac arrhythmias. They also have activity against the parasitic protozoan Trypanosoma cruzi, the causative agent of Chagas' disease. They function by disrupting intracellular Ca(2+) homeostasis of the parasite and b...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023776/ https://ncbi.nlm.nih.gov/pubmed/24492373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01240-13 |
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