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A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response
Ricin activates the proinflammatory ribotoxic stress response through the mitogen activated protein 3 kinase (MAP3K) ZAK, resulting in activation of mitogen activated protein kinases (MAPKs) p38 and JNK1/2. We had a novel zak−/− mouse generated to study the role of ZAK signaling in vivo during ricin...
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| Publicado en: | Toxins (Basel) |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5037485/ https://ncbi.nlm.nih.gov/pubmed/27598200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins8090259 |
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