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Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation

Infection with enterohemorrhagic Escherichia coli (EHEC) can result in severe disease, including hemorrhagic colitis and the hemolytic uremic syndrome. Shiga toxins (Stx) are the key EHEC virulence determinant contributing to severe disease. Despite inhibiting protein synthesis, Shiga toxins paradox...

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發表在:Infect Immun
Main Authors: Jandhyala, Dakshina M., Ahluwalia, Amrita, Schimmel, Jennifer J., Rogers, Arlin B., Leong, John M., Thorpe, Cheleste M.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694011/
https://ncbi.nlm.nih.gov/pubmed/26483408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00977-15
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