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Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation

Infection with enterohemorrhagic Escherichia coli (EHEC) can result in severe disease, including hemorrhagic colitis and the hemolytic uremic syndrome. Shiga toxins (Stx) are the key EHEC virulence determinant contributing to severe disease. Despite inhibiting protein synthesis, Shiga toxins paradox...

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書誌詳細
出版年:Infect Immun
主要な著者: Jandhyala, Dakshina M., Ahluwalia, Amrita, Schimmel, Jennifer J., Rogers, Arlin B., Leong, John M., Thorpe, Cheleste M.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694011/
https://ncbi.nlm.nih.gov/pubmed/26483408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00977-15
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