Shiga Toxin 1 Triggers a Ribotoxic Stress Response Leading to p38 and JNK Activation and Induction of Apoptosis in Intestinal Epithelial Cells

Shiga toxins made by Shiga toxin-producing Escherichia coli (STEC) are associated with hemolytic uremic syndrome. Shiga toxins (Stxs) may access the host systemic circulation by absorption across the intestinal epithelium. The effects of Stxs on this cell layer are not completely understood, althoug...

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Detalhes bibliográficos
Main Authors: Smith, Wendy E., Kane, Anne V., Campbell, Sausan T., Acheson, David W. K., Cochran, Brent H., Thorpe, Cheleste M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148871/
https://ncbi.nlm.nih.gov/pubmed/12595468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.3.1497-1504.2003
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