Shiga Toxin 2 and Flagellin from Shiga-Toxigenic Escherichia coli Superinduce Interleukin-8 through Synergistic Effects on Host Stress-Activated Protein Kinase Activation

Shiga toxins expressed in the intestinal lumen during infection with Shiga-toxigenic Escherichia coli must translocate across the epithelium and enter the systemic circulation to cause systemic (pathological) effects, including hemolytic uremic syndrome. The transepithelial migration of polymorphonu...

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Main Authors: Jandhyala, Dakshina M., Rogers, Trisha J., Kane, Anne, Paton, Adrienne W., Paton, James C., Thorpe, Cheleste M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897377/
https://ncbi.nlm.nih.gov/pubmed/20439475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00383-10
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