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Tissue Factor-Dependent Procoagulant Activity of Subtilase Cytotoxin, a Potent AB(5) Toxin Produced by Shiga Toxigenic Escherichia coli

Subtilase cytotoxin (SubAB), produced by certain virulent Shiga toxigenic Escherichia coli strains, causes hemolytic uremic syndrome-like pathology in mice, including extensive microvascular thrombosis. SubAB acts by specifically cleaving the essential endoplasmic reticulum chaperone BiP. BiP has be...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Wang, Hui, Paton, James C., Thorpe, Cheleste M., Bonder, Claudine S., Sun, Wai Yan, Paton, Adrienne W.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949535/
https://ncbi.nlm.nih.gov/pubmed/20874089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656534
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