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Tissue Factor-Dependent Procoagulant Activity of Subtilase Cytotoxin, a Potent AB(5) Toxin Produced by Shiga Toxigenic Escherichia coli

Subtilase cytotoxin (SubAB), produced by certain virulent Shiga toxigenic Escherichia coli strains, causes hemolytic uremic syndrome-like pathology in mice, including extensive microvascular thrombosis. SubAB acts by specifically cleaving the essential endoplasmic reticulum chaperone BiP. BiP has be...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Hui, Paton, James C., Thorpe, Cheleste M., Bonder, Claudine S., Sun, Wai Yan, Paton, Adrienne W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2949535/
https://ncbi.nlm.nih.gov/pubmed/20874089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/656534
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