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Protective Immunization of Mice with an Active-Site Mutant of Subtilase Cytotoxin of Shiga Toxin-Producing Escherichia coli

We have recently described a novel AB(5) cytotoxin produced by certain Shiga toxin-producing Escherichia coli strains. The A subunit of this toxin is a subtilase-like serine protease, while the B pentamer mediates binding to host cell glycolipid receptors. The subtilase cytotoxin is lethal for mice,...

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書誌詳細
主要な著者: Talbot, Ursula M., Paton, James C., Paton, Adrienne W.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2005
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168599/
https://ncbi.nlm.nih.gov/pubmed/15972544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4432-4436.2005
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