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Protective Immunization of Mice with an Active-Site Mutant of Subtilase Cytotoxin of Shiga Toxin-Producing Escherichia coli
We have recently described a novel AB(5) cytotoxin produced by certain Shiga toxin-producing Escherichia coli strains. The A subunit of this toxin is a subtilase-like serine protease, while the B pentamer mediates binding to host cell glycolipid receptors. The subtilase cytotoxin is lethal for mice,...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168599/ https://ncbi.nlm.nih.gov/pubmed/15972544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.7.4432-4436.2005 |
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