Shiga toxin type-2 (Stx2) induces glutamate release via phosphoinositide 3-kinase (PI3K) pathway in murine neurons

Por Obata, Fumiko, Hippler, Lauren M., Saha, Progyaparamita, Jandhyala, Dakshina M., Latinovic, Olga S.
Publicado no Front Mol Neurosci (2015)

Shiga Toxin 2 and Flagellin from Shiga-Toxigenic Escherichia coli Superinduce Interleukin-8 through Synergistic Effects on Host Stress-Activated Protein Kinase Activation

Por Jandhyala, Dakshina M., Rogers, Trisha J., Kane, Anne, Paton, Adrienne W., Paton, James C., Thorpe, Cheleste M.
Publicado em 2010

Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation

Por Jandhyala, Dakshina M., Ahluwalia, Amrita, Schimmel, Jennifer J., Rogers, Arlin B., Leong, John M., Thorpe, Cheleste M.
Publicado no Infect Immun (2015)

A Novel Zak Knockout Mouse with a Defective Ribotoxic Stress Response

Por Jandhyala, Dakshina M., Wong, John, Mantis, Nicholas J., Magun, Bruce E., Leong, John M., Thorpe, Cheleste M.
Publicado no Toxins (Basel) (2016)

Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways

Por Wolfson, Jennifer J., May, Kerrie L., Thorpe, Cheleste M., Jandhyala, Dakshina M., Paton, James C., Paton, Adrienne W.
Publicado em 2008

Shiga Toxin–Producing Escherichia coli O104:H4: An Emerging Pathogen with Enhanced Virulence

Por Jandhyala, Dakshina M., Vanguri, Vijay, Boll, Erik J., Lai, YuShuan, McCormick, Beth A., Leong, John M.
Publicado em 2013

Prevalence of the Operon Encoding Subtilase Cytotoxin in Non-O157 Shiga Toxin-Producing Escherichia coli Isolated from Humans in the United States

Por Wolfson, Jennifer J., Jandhyala, Dakshina M., Gorczyca, Lynn A., Qadeer, Zulekha, Manning, Shannon D., Hadler, James, Rudrik, James T., Thorpe, Cheleste M.
Publicado em 2009

Effects of Shiga Toxin Type 2 on a Bioengineered Three-Dimensional Model of Human Renal Tissue

Por DesRochers, Teresa M., Kimmerling, Erica Palma, Jandhyala, Dakshina M., El-Jouni, Wassim, Zhou, Jing, Thorpe, Cheleste M., Leong, John M., Kaplan, David L.
Publicado no Infect Immun (2014)

Small molecule kinase inhibitors block the ZAK-dependent inflammatory effects of doxorubicin

Por Wong, John, Smith, Logan B., Magun, Eli A., Engstrom, Thomas, Kelley-Howard, Kirsten, Jandhyala, Dakshina M., Thorpe, Cheleste M., Magun, Bruce E., Wood, Lisa J.
Publicado em 2013

Shiga toxin 2-induced intestinal pathology in infant rabbits is A-subunit dependent and responsive to the tyrosine kinase and potential ZAK inhibitor imatinib

Por Stone, Samuel M., Thorpe, Cheleste M., Ahluwalia, Amrita, Rogers, Arlin B., Obata, Fumiko, Vozenilek, Aimee, Kolling, Glynis L., Kane, Anne V., Magun, Bruce E., Jandhyala, Dakshina M.
Publicado em 2012

Natural killer T (NKT) cells accelerate Shiga toxin type 2 (Stx2) pathology in mice

Por Obata, Fumiko, Subrahmanyam, Priyanka B., Vozenilek, Aimee E., Hippler, Lauren M., Jeffers, Tynae, Tongsuk, Methinee, Tiper, Irina, Saha, Progyaparamita, Jandhyala, Dakshina M., Kolling, Glynis L., Latinovic, Olga, Webb, Tonya J.
Publicado no Front Microbiol (2015)