Effects of Shiga Toxin Type 2 on a Bioengineered Three-Dimensional Model of Human Renal Tissue

Shiga toxins (Stx) are a family of cytotoxic proteins that can cause hemolytic-uremic syndrome (HUS), a thrombotic microangiopathy, following infections by Shiga toxin-producing Escherichia coli (STEC). Renal failure is a key feature of HUS and a major cause of childhood renal failure worldwide. The...

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Publicado en:Infect Immun
Autores principales: DesRochers, Teresa M., Kimmerling, Erica Palma, Jandhyala, Dakshina M., El-Jouni, Wassim, Zhou, Jing, Thorpe, Cheleste M., Leong, John M., Kaplan, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2014
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288879/
https://ncbi.nlm.nih.gov/pubmed/25312954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02143-14
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