Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation

Infection with enterohemorrhagic Escherichia coli (EHEC) can result in severe disease, including hemorrhagic colitis and the hemolytic uremic syndrome. Shiga toxins (Stx) are the key EHEC virulence determinant contributing to severe disease. Despite inhibiting protein synthesis, Shiga toxins paradox...

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Foilsithe in:Infect Immun
Main Authors: Jandhyala, Dakshina M., Ahluwalia, Amrita, Schimmel, Jennifer J., Rogers, Arlin B., Leong, John M., Thorpe, Cheleste M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Host Response and Inflammation
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694011/
https://ncbi.nlm.nih.gov/pubmed/26483408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00977-15
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