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ZAK is required for doxorubicin, a novel ribotoxic stressor, to induce SAPK activation and apoptosis in HaCaT cells

Doxorubicin is an anthracycline drug that is one of the most effective and widely used anticancer agents for the treatment of both hematologic and solid tumors. The stress-activated protein kinases (SAPKs) are frequently activated by a number of cancer chemotherapeutics. When phosphorylated, the SAP...

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Detaylı Bibliyografya
Asıl Yazarlar: Sauter, Kristin AD, Magun, Eli A, Iordanov, Mihail S, Magun, Bruce E
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3040836/
https://ncbi.nlm.nih.gov/pubmed/20559024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.10.3.12367
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