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The dynamics of genomic-length DNA molecules in 100-nm channels

We show that genomic-length DNA molecules imaged in nanochannels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers. This fundamental relationship allows u...

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Autori principali: Tegenfeldt, Jonas O., Prinz, Christelle, Cao, Han, Chou, Steven, Reisner, Walter W., Riehn, Robert, Wang, Yan Mei, Cox, Edward C., Sturm, James C., Silberzan, Pascal, Austin, Robert H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC503729/
https://ncbi.nlm.nih.gov/pubmed/15252203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0403849101
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