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Single-molecule studies of repressor–DNA interactions show long-range interactions
We have performed single-molecule studies of GFP–LacI repressor proteins bound to bacteriophage λ DNA containing a 256 tandem lac operator insertion confined in nanochannels. An integrated photon molecular counting method was developed to determine the number of proteins bound to DNA. By using this...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1168954/ https://ncbi.nlm.nih.gov/pubmed/15994229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0502917102 |
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