The dynamics of genomic-length DNA molecules in 100-nm channels

We show that genomic-length DNA molecules imaged in nanochannels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers. This fundamental relationship allows u...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Tegenfeldt, Jonas O., Prinz, Christelle, Cao, Han, Chou, Steven, Reisner, Walter W., Riehn, Robert, Wang, Yan Mei, Cox, Edward C., Sturm, James C., Silberzan, Pascal, Austin, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503729/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252203/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403849101
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