The dynamics of genomic-length DNA molecules in 100-nm channels

We show that genomic-length DNA molecules imaged in nanochannels have an extension along the channel that scales linearly with the contour length of the polymer, in agreement with the scaling arguments developed by de Gennes for self-avoiding confined polymers. This fundamental relationship allows u...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Tegenfeldt, Jonas O., Prinz, Christelle, Cao, Han, Chou, Steven, Reisner, Walter W., Riehn, Robert, Wang, Yan Mei, Cox, Edward C., Sturm, James C., Silberzan, Pascal, Austin, Robert H.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2004
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC503729/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15252203/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0403849101
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