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Robust and Accurate Discrimination of Self/Non-Self Antigen Presentations by Regulatory T Cell Suppression

The immune response by T cells usually discriminates self and non-self antigens, even though the negative selection of self-reactive T cells is imperfect and a certain fraction of T cells can respond to self-antigens. In this study, we construct a simple mathematical model of T cell populations to a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Furusawa, Chikara, Yamaguchi, Tomoyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036821/
https://ncbi.nlm.nih.gov/pubmed/27668873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163134
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