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A20 Is an Antigen Presentation Attenuator and Its Inhibition Supersedes Regulatory T Cell-Mediated Suppression
Regulatory T cells (T(reg)) suppress autoreactive immune responses and limit the efficacy of tumor vaccines; however, it remains a challenge to selectively eliminate or inhibit T(reg). In this study, A20, a negative regulator of the TLR and TNFR signaling pathways, was found to play a critical role...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3684168/ https://ncbi.nlm.nih.gov/pubmed/18311150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1721 |
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