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A20 Is an Antigen Presentation Attenuator and Its Inhibition Supersedes Regulatory T Cell-Mediated Suppression

Regulatory T cells (T(reg)) suppress autoreactive immune responses and limit the efficacy of tumor vaccines; however, it remains a challenge to selectively eliminate or inhibit T(reg). In this study, A20, a negative regulator of the TLR and TNFR signaling pathways, was found to play a critical role...

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שמור ב:
מידע ביבליוגרפי
Main Authors: Song, Xiao-Tong, Kabler, Kevin Evel, Shen, Lei, Rollins, Lisa, Huang, Xue F, Chen, Si-Yi
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3684168/
https://ncbi.nlm.nih.gov/pubmed/18311150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm1721
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