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Robust discrimination between self and non-self neurites requires thousands of Dscam1 isoforms
Down Syndrome cell adhesion molecule(Dscam) genes encode neuronal cell recognition proteins of the immunoglobulin superfamily1,2. In Drosophila, Dscam1 generates 19,008 different ecto-domains by alternative splicing of three exon clusters, each encoding half or a complete variable immunoglobulin dom...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836808/ https://ncbi.nlm.nih.gov/pubmed/19794492 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08431 |
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