Robust discrimination between self and non-self neurites requires thousands of Dscam1 isoforms

Down Syndrome cell adhesion molecule(Dscam) genes encode neuronal cell recognition proteins of the immunoglobulin superfamily1,2. In Drosophila, Dscam1 generates 19,008 different ecto-domains by alternative splicing of three exon clusters, each encoding half or a complete variable immunoglobulin dom...

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Bibliografiske detaljer
Main Authors: Hattori, Daisuke, Chen, Yi, Matthews, Benjamin J., Salwinski, Lukasz, Sabatti, Chiara, Grueber, Wesley B., Zipursky, S. Lawrence
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836808/
https://ncbi.nlm.nih.gov/pubmed/19794492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08431
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