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Theoretical modeling reveals that regulatory T cells increase T-cell interaction with antigen-presenting cells for stable immune tolerance
The immune system in tolerance maintains cell diversity without responding to self-antigens. Foxp3-expressing CD25(+)CD4(+) regulatory T cells (Tregs) inhibit T-cell activation through various molecular mechanisms. However, several key questions are still not resolved, including how Tregs control th...
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| Gepubliceerd in: | Int Immunol |
|---|---|
| Hoofdauteurs: | , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Oxford University Press
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6794947/ https://ncbi.nlm.nih.gov/pubmed/31131864 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxz043 |
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