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Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives
Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive monogenic disease worldwide. These mutations alter the synthesis, processing, function, or half-life of CFTR, the main chloride channel expressed in the apical membrane of epithelial cells in the airway, intestine, panc...
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| Опубликовано в: : | Clin Pharmacol |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Dove Medical Press
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036583/ https://ncbi.nlm.nih.gov/pubmed/27703398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S100759 |
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