Cystic fibrosis transmembrane conductance regulator modulators in cystic fibrosis: current perspectives

Mutations of the CFTR gene cause cystic fibrosis (CF), the most common recessive monogenic disease worldwide. These mutations alter the synthesis, processing, function, or half-life of CFTR, the main chloride channel expressed in the apical membrane of epithelial cells in the airway, intestine, panc...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Clin Pharmacol
Asıl Yazarlar: Schmidt, Béla Z, Haaf, Jérémy B, Leal, Teresinha, Noel, Sabrina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Dove Medical Press 2016
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5036583/
https://ncbi.nlm.nih.gov/pubmed/27703398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/CPAA.S100759
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