Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator

BACKGROUND AND PURPOSE: Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel. In the search for new CF therapies, small molecules have been identified that rescue the defective channel gating of CF mutants (termed CFTR potentia...

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Hlavní autoři: Schmidt, A, Hughes, L K, Cai, Z, Mendes, F, Li, H, Sheppard, D N, Amaral, M D
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2008
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275442/
https://ncbi.nlm.nih.gov/pubmed/18223673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707663
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