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Prolonged treatment of cells with genistein modulates the expression and function of the cystic fibrosis transmembrane conductance regulator
BACKGROUND AND PURPOSE: Cystic fibrosis (CF) is caused by dysfunction of the cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channel. In the search for new CF therapies, small molecules have been identified that rescue the defective channel gating of CF mutants (termed CFTR potentia...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2275442/ https://ncbi.nlm.nih.gov/pubmed/18223673 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707663 |
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