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The Closing Mechanism of DNA Polymerase I at Atomic Resolution
DNA polymerases must quickly and accurately distinguish between similar nucleic acids to form Watson-Crick base pairs and avoid DNA replication errors. Deoxynucleoside triphosphate (dNTP) binding to the DNA polymerase active site induces a large conformational change that is difficult to characteriz...
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| Publicado no: | Structure |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5036450/ https://ncbi.nlm.nih.gov/pubmed/26211612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.06.016 |
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