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The Mechanism of the Translocation Step in DNA Replication by DNA Polymerase I: A Computer Simulation Analysis
High-fidelity DNA polymerases copy DNA rapidly and accurately by adding correct deoxynucleotide triphosphates to a growing primer strand of DNA. Following nucleotide incorporation, a series of conformational changes translocate the DNA substrate by one base pair step, readying the polymerase for the...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3325112/ https://ncbi.nlm.nih.gov/pubmed/20152155 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2009.10.014 |
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