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In B cells, phosphatidylinositol 5-phosphate 4-kinase–α synthesizes PI(4,5)P(2) to impact mTORC2 and Akt signaling
Phosphatidylinositol 5-phosphate 4-kinases (PI5P4Ks) are enigmatic lipid kinases with physiological functions that are incompletely understood, not the least because genetic deletion and cell transfection have led to contradictory data. Here, we used the genetic tractability of DT40 cells to create...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5035885/ https://ncbi.nlm.nih.gov/pubmed/27601656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522478113 |
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