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Activation of phosphatidylinositol 4,5-bisphosphate supply by agonists and non-hydrolysable GTP analogues.

PtdIns(4,5)P2 serves as a precursor of a diverse family of signalling molecules, including diacylglycerol (and hence phosphatidic acid), Ins(1,4,5)P3 [and hence Ins(1,3,4,5)P4] and PtdIns(3,4,5)P3. The production of these messengers can be activated by agonists, and therefore the rate of utilization...

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Detalhes bibliográficos
Main Authors: Stephens, L, Jackson, T R, Hawkins, P T
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1137720/
https://ncbi.nlm.nih.gov/pubmed/8257441
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