Pericyte–fibroblast transition promotes tumor growth and metastasis

Vascular pericytes, an important cellular component in the tumor microenvironment, are often associated with tumor vasculatures, and their functions in cancer invasion and metastasis are poorly understood. Here we show that PDGF-BB induces pericyte–fibroblast transition (PFT), which significantly co...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Hosaka, Kayoko, Yang, Yunlong, Seki, Takahiro, Fischer, Carina, Dubey, Olivier, Fredlund, Erik, Hartman, Johan, Religa, Piotr, Morikawa, Hiromasa, Ishii, Yoko, Sasahara, Masakiyo, Larsson, Ola, Cossu, Giulio, Cao, Renhai, Lim, Sharon, Cao, Yihai
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
PNAS Plus
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035870/
https://ncbi.nlm.nih.gov/pubmed/27608497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608384113
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