Pericyte–fibroblast transition promotes tumor growth and metastasis

Vascular pericytes, an important cellular component in the tumor microenvironment, are often associated with tumor vasculatures, and their functions in cancer invasion and metastasis are poorly understood. Here we show that PDGF-BB induces pericyte–fibroblast transition (PFT), which significantly co...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Hosaka, Kayoko, Yang, Yunlong, Seki, Takahiro, Fischer, Carina, Dubey, Olivier, Fredlund, Erik, Hartman, Johan, Religa, Piotr, Morikawa, Hiromasa, Ishii, Yoko, Sasahara, Masakiyo, Larsson, Ola, Cossu, Giulio, Cao, Renhai, Lim, Sharon, Cao, Yihai
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035870/
https://ncbi.nlm.nih.gov/pubmed/27608497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608384113
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