Pericyte–fibroblast transition promotes tumor growth and metastasis

Vascular pericytes, an important cellular component in the tumor microenvironment, are often associated with tumor vasculatures, and their functions in cancer invasion and metastasis are poorly understood. Here we show that PDGF-BB induces pericyte–fibroblast transition (PFT), which significantly co...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Hosaka, Kayoko, Yang, Yunlong, Seki, Takahiro, Fischer, Carina, Dubey, Olivier, Fredlund, Erik, Hartman, Johan, Religa, Piotr, Morikawa, Hiromasa, Ishii, Yoko, Sasahara, Masakiyo, Larsson, Ola, Cossu, Giulio, Cao, Renhai, Lim, Sharon, Cao, Yihai
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2016
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5035870/
https://ncbi.nlm.nih.gov/pubmed/27608497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1608384113
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