The PDGF-BB-SOX7 axis-modulated IL-33 in pericytes and stromal cells promotes metastasis through tumour-associated macrophages

Signalling molecules and pathways that mediate crosstalk between various tumour cellular compartments in cancer metastasis remain largely unknown. We report a mechanism of the interaction between perivascular cells and tumour-associated macrophages (TAMs) in promoting metastasis through the IL-33–ST...

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Publicado no:Nat Commun
Main Authors: Yang, Yunlong, Andersson, Patrik, Hosaka, Kayoko, Zhang, Yin, Cao, Renhai, Iwamoto, Hideki, Yang, Xiaojuan, Nakamura, Masaki, Wang, Jian, Zhuang, Rujie, Morikawa, Hiromasa, Xue, Yuan, Braun, Harald, Beyaert, Rudi, Samani, Nilesh, Nakae, Susumu, Hams, Emily, Dissing, Steen, Fallon, Padraic G., Langer, Robert, Cao, Yihai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859070/
https://ncbi.nlm.nih.gov/pubmed/27150562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11385
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