Endothelial PDGF-CC regulates angiogenesis-dependent thermogenesis in beige fat

Cold- and β3-adrenoceptor agonist-induced sympathetic activation leads to angiogenesis and UCP1-dependent thermogenesis in mouse brown and white adipose tissues. Here we show that endothelial production of PDGF-CC during white adipose tissue (WAT) angiogenesis regulates WAT browning. We find that ge...

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Publicado no:Nat Commun
Main Authors: Seki, Takahiro, Hosaka, Kayoko, Lim, Sharon, Fischer, Carina, Honek, Jennifer, Yang, Yunlong, Andersson, Patrik, Nakamura, Masaki, Näslund, Erik, Ylä-Herttuala, Seppo, Sun, Meili, Iwamoto, Hideki, Li, Xuri, Liu, Yizhi, Samani, Nilesh J., Cao, Yihai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980448/
https://ncbi.nlm.nih.gov/pubmed/27492130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12152
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