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Malignant cell-derived PlGF promotes normalization and remodeling of the tumor vasculature
Vascular functions of PlGF remain poorly understood and controversial. Here, we show that tumor cell-derived PlGF-1 and PlGF-2 displayed significant remodeling effects on the tumor vasculature, leading to a normalized vascular phenotype and improved functions against leakage. In two murine tumor mod...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2752403/ https://ncbi.nlm.nih.gov/pubmed/19805167 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0908026106 |
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